3p3e | pdb_00003p3e

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Template:STRUCTURE 3p3e

Crystal Structure of the PSEUDOMONAS AERUGINOSA LpxC/LPC-009 complex

Template:ABSTRACT PUBMED 21167751

Function

[LPXC_PSEAE] Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

About this Structure

3p3e is a 1 chain structure with sequence from Pseudomonas aeruginosa. Full crystallographic information is available from OCA.

Reference

  1. Lee CJ, Liang X, Chen X, Zeng D, Joo SH, Chung HS, Barb AW, Swanson SM, Nicholas RA, Li Y, Toone EJ, Raetz CR, Zhou P. Species-Specific and Inhibitor-Dependent Conformations of LpxC: Implications for Antibiotic Design. Chem Biol. 2010 Dec 16. PMID:21167751 doi:10.1016/j.chembiol.2010.11.011

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