3pm6 | pdb_00003pm6

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Template:STRUCTURE 3pm6

Crystal structure of a putative fructose-1,6-biphosphate aldolase from Coccidioides immitis solved by combined SAD MR

Template:ABSTRACT PUBMED 21359836

Function

[ALF_COCIM] Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis (By similarity).

About this Structure

3pm6 is a 2 chain structure with sequence from Coccidioides immitis. Full crystallographic information is available from OCA.

Reference

  1. Abendroth J, Gardberg AS, Robinson JI, Christensen JS, Staker BL, Myler PJ, Stewart LJ, Edwards TE. SAD phasing using iodide ions in a high-throughput structural genomics environment. J Struct Funct Genomics. 2011 Jul;12(2):83-95. Epub 2011 Feb 27. PMID:21359836 doi:10.1007/s10969-011-9101-7

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