3ptd | pdb_00003ptd

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Template:STRUCTURE 3ptd

PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C MUTANT D274S

Template:ABSTRACT PUBMED 9335537

Function

[PLC_BACCE] Cleaves glycosylphosphatidylinositol (GPI) and phosphatidylinositol (PI) anchors but not PI phosphates.

About this Structure

3ptd is a 1 chain structure with sequence from Bacillus cereus. Full crystallographic information is available from OCA.

Reference

  1. Gassler CS, Ryan M, Liu T, Griffith OH, Heinz DW. Probing the roles of active site residues in phosphatidylinositol-specific phospholipase C from Bacillus cereus by site-directed mutagenesis. Biochemistry. 1997 Oct 21;36(42):12802-13. PMID:9335537 doi:10.1021/bi971102d

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OCA

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