3q0c | pdb_00003q0c
From Proteopedia
Crystal structure of SUVH5 SRA-fully methylated CG DNA complex in space group P6122
Function
[SUVH5_ARATH] Histone methyltransferase. Methylates 'Lys-9' of histone H3. H3 'Lys-9' methylation represents a specific tag for epigenetic transcriptional repression.
About this Structure
3q0c is a 4 chain structure with sequence from Arabidopsis thaliana. Full crystallographic information is available from OCA.
Reference
- Rajakumara E, Law JA, Simanshu DK, Voigt P, Johnson LM, Reinberg D, Patel DJ, Jacobsen SE. A dual flip-out mechanism for 5mC recognition by the Arabidopsis SUVH5 SRA domain and its impact on DNA methylation and H3K9 dimethylation in vivo. Genes Dev. 2011 Jan 15;25(2):137-52. PMID:21245167 doi:10.1101/gad.1980311
