3s8r | pdb_00003s8r

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Template:STRUCTURE 3s8r

Crystal Structures of Glutaryl 7-Aminocephalosporanic Acid Acylase: Insight into Autoproteolytic Activation

Template:ABSTRACT PUBMED 12680762

Function

[G7AC_PSEU7] Catalyzes the deacylation of 7 beta-(4-carboxybutanamido)cephalosporanic acid (glutaryl-7-aminocephalosporanic acid or GL-7-ACA) to 7-aminocephalosporanic acid (7-ACA).[1]

About this Structure

3s8r is a 2 chain structure with sequence from Pseudomonas. This structure supersedes the now removed PDB entry 1oqz. Full crystallographic information is available from OCA.

Reference

  1. Kim JK, Yang IS, Rhee S, Dauter Z, Lee YS, Park SS, Kim KH. Crystal structures of glutaryl 7-aminocephalosporanic acid acylase: insight into autoproteolytic activation. Biochemistry. 2003 Apr 15;42(14):4084-93. PMID:12680762 doi:10.1021/bi027181x
  1. ↑ Matsuda A, Komatsu KI. Molecular cloning and structure of the gene for 7 beta-(4-carboxybutanamido)cephalosporanic acid acylase from a Pseudomonas strain. J Bacteriol. 1985 Sep;163(3):1222-8. PMID:2993240

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