4edf | pdb_00004edf

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Template:STRUCTURE 4edf

Dimeric hUGDH, K94E

Template:ABSTRACT PUBMED 23106432

Function

[UGDH_HUMAN] Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate.

About this Structure

4edf is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Sennett NC, Kadirvelraj R, Wood ZA. Cofactor Binding Triggers a Molecular Switch To Allosterically Activate Human UDP-alpha-d-glucose 6-Dehydrogenase. Biochemistry. 2012 Nov 20;51(46):9364-74. doi: 10.1021/bi301067w. Epub 2012 Nov, 8. PMID:23106432 doi:10.1021/bi301067w

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