3q0m | pdb_00003q0m
From Proteopedia
Crystal structure of the PUMILIO-homology domain from Human PUMILIO1 in complex with p38alpha NREb
Template:ABSTRACT PUBMED 21397187
Function
[PUM1_HUMAN] Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of mRNA targets. May be required to support proliferation and self-renewal of stem cells (By similarity).
About this Structure
3q0m is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Lu G, Hall TM. Alternate modes of cognate RNA recognition by human PUMILIO proteins. Structure. 2011 Mar 9;19(3):361-7. PMID:21397187 doi:10.1016/j.str.2010.12.019
