3s5b | pdb_00003s5b

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Template:STRUCTURE 3s5b

Crystal Structure of CED-3 Protease Suppressor-6 (CPS-6) from Caenorhabditis elegans

Template:ABSTRACT PUBMED 22223640

Function

[NUCG_CAEEL] Endonuclease important for programmed cell death; it mediates apoptotic DNA fragmentation.

About this Structure

3s5b is a 2 chain structure with sequence from Caenorhabditis elegans. Full crystallographic information is available from OCA.

Reference

  1. Lin JL, Nakagawa A, Lin CL, Hsiao YY, Yang WZ, Wang YT, Doudeva LG, Skeen-Gaar RR, Xue D, Yuan HS. Structural insights into apoptotic DNA degradation by CED-3 protease suppressor-6 (CPS-6) from Caenorhabditis elegans. J Biol Chem. 2012 Mar 2;287(10):7110-20. Epub 2012 Jan 5. PMID:22223640 doi:10.1074/jbc.M111.316075

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OCA

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