4jx6 | pdb_00004jx6

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Template:STRUCTURE 4jx6

Structure of the carboxyl transferase domain Y628A from Rhizobium etli pyruvate carboxylase with pyruvate

Template:ABSTRACT PUBMED 23698000

Function

[Q2K340_RHIEC] Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity).[PIRNR:PIRNR001594]

About this Structure

4jx6 is a 4 chain structure with sequence from Rhizobium etli cfn 42. Full crystallographic information is available from OCA.

Reference

  1. Lietzan AD, St Maurice M. A substrate-induced biotin binding pocket in the carboxyl transferase domain of pyruvate carboxylase. J Biol Chem. 2013 May 22. PMID:23698000 doi:10.1074/jbc.M113.477828

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