3t6b | pdb_00003t6b

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Template:STRUCTURE 3t6b

Structure of human DPPIII in complex with the opioid peptide Tynorphin, at 2.4 Angstroms

Template:ABSTRACT PUBMED 22493238

Function

[DPP3_HUMAN] Cleaves Arg-Arg-beta-naphthylamide.

About this Structure

3t6b is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Bezerra GA, Dobrovetsky E, Viertlmayr R, Dong A, Binter A, Abramic M, Macheroux P, Dhe-Paganon S, Gruber K. Entropy-driven binding of opioid peptides induces a large domain motion in human dipeptidyl peptidase III. Proc Natl Acad Sci U S A. 2012 Apr 24;109(17):6525-30. Epub 2012 Apr 9. PMID:22493238 doi:10.1073/pnas.1118005109

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OCA

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