3ef0 | pdb_00003ef0

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Template:STRUCTURE 3ef0

The Structure of Fcp1, an essential RNA polymerase II CTD phosphatase

Template:ABSTRACT PUBMED 19026779

Function

[FCP1_SCHPO] Processively dephosphorylates 'Ser-2' and 'Ser-5' of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit. This promotes the activity of RNA polymerase II.

About this Structure

3ef0 is a 1 chain structure with sequence from Schizosaccharomyces pombe. Full crystallographic information is available from OCA.

Reference

  1. Ghosh A, Shuman S, Lima CD. The structure of Fcp1, an essential RNA polymerase II CTD phosphatase. Mol Cell. 2008 Nov 21;32(4):478-90. PMID:19026779 doi:10.1016/j.molcel.2008.09.021

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