4axl | pdb_00004axl

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Template:STRUCTURE 4axl

HUMAN CATHEPSIN L APO FORM WITH ZN

Template:ABSTRACT PUBMED 23658062

Function

[CATL1_HUMAN] Important for the overall degradation of proteins in lysosomes.

About this Structure

4axl is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Ehmke V, Winkler E, Banner DW, Haap W, Schweizer WB, Rottmann M, Kaiser M, Freymond C, Schirmeister T, Diederich F. Optimization of Triazine Nitriles as Rhodesain Inhibitors: Structure-Activity Relationships, Bioisosteric Imidazopyridine Nitriles, and X-ray Crystal Structure Analysis with Human Cathepsin L. ChemMedChem. 2013 Jun;8(6):967-75. doi: 10.1002/cmdc.201300112. Epub 2013 May 9. PMID:23658062 doi:10.1002/cmdc.201300112

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