2lou | pdb_00002lou
From Proteopedia
AR55 solubilised in DPC micelles
Function
[APJ_HUMAN] Receptor for apelin coupled to G proteins that inhibit adenylate cyclase activity. Alternative coreceptor with CD4 for HIV-1 infection; may be involved in the development of AIDS dementia.
About this Structure
2lou is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA.
Reference
- Langelaan DN, Reddy T, Banks AW, Dellaire G, Dupre DJ, Rainey JK. Structural features of the apelin receptor N-terminal tail and first transmembrane segment implicated in ligand binding and receptor trafficking. Biochim Biophys Acta. 2013 Jun;1828(6):1471-83. doi:, 10.1016/j.bbamem.2013.02.005. Epub 2013 Feb 22. PMID:23438363 doi:10.1016/j.bbamem.2013.02.005
