3lw2 | pdb_00003lw2
From Proteopedia
Mouse Plasminogen Activator Inhibitor-1 (PAI-1)
Function
[PAI1_MOUSE] Serine protease inhibitor. This inhibitor acts as 'bait' for tissue plasminogen activator, urokinase, protein C and matriptase-3/TMPRSS7. Its rapid interaction with PLAT may function as a major control point in the regulation of fibrinolysis (By similarity).
About this Structure
3lw2 is a 1 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.
Reference
- Dewilde M, Van De Craen B, Compernolle G, Madsen JB, Strelkov S, Gils A, Declerck PJ. Subtle structural differences between human and mouse PAI-1 reveal the basis for biochemical differences. J Struct Biol. 2010 Mar 15. PMID:20230900 doi:10.1016/j.jsb.2010.03.006
