4g59 | pdb_00004g59

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Template:STRUCTURE 4g59

Crystal structure of the murine cytomegalovirus MHC-I homolog m152 with ligand RAE-1 gamma

Template:ABSTRACT PUBMED 23169621

Function

[RAE1C_MOUSE] Acts as a ligand for NKG2D.[1]

About this Structure

4g59 is a 4 chain structure with sequence from Murid herpesvirus 1 and Mus musculus. Full crystallographic information is available from OCA.

Reference

  1. Wang R, Natarajan K, Revilleza MJ, Boyd LF, Zhi L, Zhao H, Robinson H, Margulies DH. Structural basis of mouse cytomegalovirus m152/gp40 interaction with RAE1gamma reveals a paradigm for MHC/MHC interaction in immune evasion. Proc Natl Acad Sci U S A. 2012 Nov 19. PMID:23169621 doi:10.1073/pnas.1214088109
  1. ↑ Cerwenka A, Bakker AB, McClanahan T, Wagner J, Wu J, Phillips JH, Lanier LL. Retinoic acid early inducible genes define a ligand family for the activating NKG2D receptor in mice. Immunity. 2000 Jun;12(6):721-7. PMID:10894171

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