CD94

<StructureSection load='3bdw' size='350' side='right' caption='Structure of CD94 (grey, pink)/NKG2 (green, yellow) heterodimer (PDB entry 3bdw)' scene=>

CD94 (or Cluster of Differentiation 94) is a lectin which is expressed on the surface of natural killer cells. CD94 makes a heterodimer with NKG2. The dimer interacts with human leukocyte antigen (HLA)-E on target cells.

3D Structures of CD94

Updated on 30-June-2013

1b6e – hCD94 C type lectin domain – human
3bdw – hCD94 C type lectin domain + NKG2
3cdg, 3cii – hCD94 C type lectin domain + NKG2 + class I MHC + β-2 microglobulin

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Michal Harel, Alexander Berchansky