4k8z | pdb_00004k8z
From Proteopedia
KOD Polymerase in binary complex with dsDNA
Function
[DPOL_PYRKO] Intein encoded endonucleases are thought to mediate intein mobility by site-specific recombination initiated by endonuclease cleavage at the "homing site" in gene that lack the intein. PI-PkoI recognizes 5'-GATTTAGATCCCTGTACC-3' and PI-PkoII recognizes 5'-CAGCTACTACGGTTAC-3'.
About this Structure
4k8z is a 3 chain structure with sequence from Thermococcus kodakarensis kod1. Full crystallographic information is available from OCA.
Reference
- Bergen K, Betz K, Welte W, Diederichs K, Marx A. Structures of KOD and 9 degrees N DNA Polymerases Complexed with Primer Template Duplex. Chembiochem. 2013 Jun 17;14(9):1058-62. doi: 10.1002/cbic.201300175. Epub 2013, Jun 3. PMID:23733496 doi:10.1002/cbic.201300175
