1e5g | pdb_00001e5g

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Template:STRUCTURE 1e5g

Solution structure of central CP module pair of a pox virus complement inhibitor

Template:ABSTRACT PUBMED 11243823

Function

[VCP_VACCC] Serves to protect the virus against complement attack by inhibiting both classical and alternative pathways of complement activation. Binds C3b and C4b.

About this Structure

1e5g is a 1 chain structure with sequence from Vaccinia virus copenhagen. Full experimental information is available from OCA.

Reference

  1. Henderson CE, Bromek K, Mullin NP, Smith BO, Uhrin D, Barlow PN. Solution structure and dynamics of the central CCP module pair of a poxvirus complement control protein. J Mol Biol. 2001 Mar 16;307(1):323-39. PMID:11243823 doi:10.1006/jmbi.2000.4477

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