3rh1 | pdb_00003rh1

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Template:STRUCTURE 3rh1

X-ray Structure of a cis-proline (P114) to alanine variant of Ribonuclease A

Template:ABSTRACT PUBMED 22273774

Function

[RNAS1_BOVIN] Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. Acts on single stranded and double stranded RNA.[1]

About this Structure

3rh1 is a 1 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA.

See Also

Reference

  1. Merlino A, Picone D, Ercole C, Balsamo A, Sica F. Chain termini cross-talk in the swapping process of bovine pancreatic ribonuclease. Biochimie. 2012 Jan 17. PMID:22273774 doi:10.1016/j.biochi.2012.01.010
  1. ↑ delCardayre SB, Ribo M, Yokel EM, Quirk DJ, Rutter WJ, Raines RT. Engineering ribonuclease A: production, purification and characterization of wild-type enzyme and mutants at Gln11. Protein Eng. 1995 Mar;8(3):261-73. PMID:7479688

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