4b9t | pdb_00004b9t

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Template:STRUCTURE 4b9t

Structure of the high fidelity DNA polymerase I with an oxidative formamidopyrimidine-dG DNA lesion -dC basepair in the post-insertion site.

Template:ABSTRACT PUBMED 23685671

About this Structure

4b9t is a 3 chain structure with sequence from Geobacillus stearothermophilus. Full crystallographic information is available from OCA.

Reference

  1. Gehrke TH, Lischke U, Gasteiger KL, Schneider S, Arnold S, Muller HC, Stephenson DS, Zipse H, Carell T. Unexpected non-Hoogsteen-based mutagenicity mechanism of FaPy-DNA lesions. Nat Chem Biol. 2013 May 19. doi: 10.1038/nchembio.1254. PMID:23685671 doi:10.1038/nchembio.1254

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OCA