3s8e | pdb_00003s8e
From Proteopedia
Phosphorylation regulates assembly of the caspase-6 substrate-binding groove
Template:ABSTRACT PUBMED 22483120
Function
[CASP6_HUMAN] Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death.
About this Structure
3s8e is a 8 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Velazquez-Delgado EM, Hardy JA. Phosphorylation regulates assembly of the caspase-6 substrate-binding groove. Structure. 2012 Apr 4;20(4):742-51. Epub 2012 Apr 3. PMID:22483120 doi:10.1016/j.str.2012.02.003
