2cfa | pdb_00002cfa

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Template:STRUCTURE 2cfa

Structure of viral flavin-dependant thymidylate synthase ThyX

Template:ABSTRACT PUBMED 16707489

Function

[THYX_PBCV1] Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity).

About this Structure

2cfa is a 2 chain structure with sequence from Paramecium bursaria chlorella virus 1. Full crystallographic information is available from OCA.

See Also

Reference

  1. Graziani S, Bernauer J, Skouloubris S, Graille M, Zhou CZ, Marchand C, Decottignies P, van Tilbeurgh H, Myllykallio H, Liebl U. Catalytic mechanism and structure of viral flavin-dependent thymidylate synthase ThyX. J Biol Chem. 2006 Aug 18;281(33):24048-57. Epub 2006 May 17. PMID:16707489 doi:10.1074/jbc.M600745200

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