1oe4 | pdb_00001oe4
From Proteopedia
Xenopus SMUG1, an anti-mutator uracil-DNA Glycosylase
Function
[SMUG1_XENLA] Responsible for recognizing base lesions in the genome and initiating base excision DNA repair. Acts as a monofunctional DNA glycosylase specific for uracil (U) residues in DNA and has a preference for single-stranded DNA substrates. No enzymatic activity towards G/T mismatches.
About this Structure
1oe4 is a 4 chain structure with sequence from Xenopus laevis. Full crystallographic information is available from OCA.
See Also
Reference
- Wibley JE, Waters TR, Haushalter K, Verdine GL, Pearl LH. Structure and specificity of the vertebrate anti-mutator uracil-DNA glycosylase SMUG1. Mol Cell. 2003 Jun;11(6):1647-59. PMID:12820976
