4iru | pdb_00004iru
From Proteopedia
Crystal Structure of lepB GAP core in a transition state mimetic complex with Rab1A and ALF3
Function
[RAB1A_HUMAN] Probably required for transit of protein from the ER through Golgi compartment. Binds GTP and GDP and possesses intrinsic GTPase activity.
About this Structure
4iru is a 6 chain structure with sequence from Homo sapiens and Legionella pneumophila subsp. pneumophila str. philadelphia 1. Full crystallographic information is available from OCA.
Reference
- Mishra AK, Del Campo CM, Collins RE, Roy CR, Lambright DG. The Legionella pneumophila GTPase Activating Protein LepB Accelerates Rab1 Deactivation by a Non-Canonical Hydrolytic Mechanism. J Biol Chem. 2013 Jul 2. PMID:23821544 doi:10.1074/jbc.M113.470625
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Homo sapiens
- Legionella pneumophila subsp. pneumophila str. philadelphia 1
- Small monomeric GTPase
- Collins, R E.
- Delcampo, C M.
- Lambright, D G.
- Mishra, A K.
- Roy, C R.
- Arginine finger
- Glutamate finger
- Gtp hydrolysis
- Gtp hydrolysis activator
- Hydrolase-hydrolase complex
- Intrinsic gtpase activity
- Nucleotide binding
- P-loop motif
- Protein transport
