4i64 | pdb_00004i64

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Template:STRUCTURE 4i64

3-hydroxy-3-methylglutaryl Coenzyme A reductase from Pseudomonas mevalonii, a high resolution native structure

Template:ABSTRACT PUBMED 23802607

Function

[MVAA_PSEMV] P.mevalonii can use mevalonate as sole carbon source. With this enzyme mevalonate is deacetylated to HMG-CoA.

About this Structure

4i64 is a 2 chain structure with sequence from Pseudomonas mevalonii. Full crystallographic information is available from OCA.

Reference

  1. Steussy CN, Critchelow CJ, Schmidt TJ, Min JK, Wrensford LV, Burgner JW, Rodwell VW, Stauffacher CV. A novel role for CoA during hydride transfer in 3-hydroxy-3-methylglutaryl-coenzyme A reductase. Biochemistry. 2013 Jun 26. PMID:23802607 doi:10.1021/bi400335g

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OCA

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