4f86 | pdb_00004f86

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Template:STRUCTURE 4f86

Structure analysis of Geranyl diphosphate methyltransferase in complex with GPP and sinefungin

Template:ABSTRACT PUBMED 23090405

Function

[GPPMT_STRLS] Catalyzes the SAM-dependent methylation of geranyl diphosphate (GPP) to yield (E)-2-methylgeranyl diphosphate (2-MeGPP).

About this Structure

4f86 is a 12 chain structure with sequence from Streptomyces lasaliensis. Full crystallographic information is available from OCA.

Reference

  1. Ariyawutthiphan O, Ose T, Minami A, Sinde S, Tsuda M, Gao YG, Yao M, Oikawa H, Tanaka I. Structure analysis of geranyl pyrophosphate methyltransferase and the proposed reaction mechanism of SAM-dependent C-methylation. Acta Crystallogr D Biol Crystallogr. 2012 Nov;68(Pt 11):1558-69. doi:, 10.1107/S0907444912038486. Epub 2012 Oct 18. PMID:23090405 doi:10.1107/S0907444912038486

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