4feu | pdb_00004feu
From Proteopedia
Crystal structure of the aminoglycoside phosphotransferase APH(3')-Ia, with substrate kanamycin and small molecule inhibitor anthrapyrazolone SP600125
About this Structure
4feu is a 6 chain structure with sequence from Acinetobacter baumannii aye. Full crystallographic information is available from OCA.
See Also
Reference
- Stogios PJ, Spanogiannopoulos P, Evdokimova E, Egorova O, Shakya T, Todorovic N, Capretta A, Wright GD, Savchenko A. Structure-guided optimization of protein kinase inhibitors reverses aminoglycoside antibiotic resistance. Biochem J. 2013 Jun 12. PMID:23758273 doi:10.1042/BJ20130317
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Acinetobacter baumannii aye
- Kanamycin kinase
- Anderson, W F.
- CSGID, Center for Structural Genomics of Infectious Diseases.
- Egorova, O.
- Evdokimova, E.
- Leo, R Di.
- Minasov, G.
- Savchenko, A.
- Shakya, T.
- Spanogiannopoulos, P.
- Stogios, P J.
- Wawrzak, Z.
- Wright, G D.
- Alpha/beta protein
- Aminoglycoside phosphotransferase
- Aminoglycoside
- Anthrapyrazolone
- Antibiotic resistance
- Center for structural genomics of infectious disease
- Csgid
- Eukaryotic protein kinase-like fold
- Gtp
- Intracellular
- Kanamycin
- National institute of allergy and infectious disease
- Niaid
- Phosphotransferase
- Protein kinase inhibitor
- Sp600125
- Transferase
- Transferase-transferase inhibitor complex
