2cgt | pdb_00002cgt

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Template:STRUCTURE 2cgt

GROEL-ADP-gp31 COMPLEX

Template:ABSTRACT PUBMED 16549073

Function

[CH60_ECOLI] Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.[HAMAP-Rule:MF_00600] Essential for the growth of the bacteria and the assembly of several bacteriophages. Also plays a role in coupling between replication of the F plasmid and cell division of the cell.[HAMAP-Rule:MF_00600] [VG31_BPT4] Essential for proper capsid assembly. In absence of Gp31 the major capsid protein (Gp23) assembles into 'lumps'. Acts as a co-chaperonin with the host groEL protein.

About this Structure

2cgt is a 21 chain structure with sequence from Enterobacteria phage t4 and Escherichia coli. Full crystallographic information is available from OCA.

See Also

Reference

  1. Clare DK, Bakkes PJ, van Heerikhuizen H, van der Vies SM, Saibil HR. An expanded protein folding cage in the GroEL-gp31 complex. J Mol Biol. 2006 May 5;358(3):905-11. Epub 2006 Mar 6. PMID:16549073 doi:10.1016/j.jmb.2006.02.033

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