1azt | pdb_00001azt

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Template:STRUCTURE 1azt

GS-ALPHA COMPLEXED WITH GTP-GAMMA-S

Template:ABSTRACT PUBMED 9395396

Function

[GNAS2_BOVIN] Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(s) protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase in response to beta-adrenergic stimuli.

About this Structure

1azt is a 2 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA.

See Also

Reference

  1. Sunahara RK, Tesmer JJ, Gilman AG, Sprang SR. Crystal structure of the adenylyl cyclase activator Gsalpha. Science. 1997 Dec 12;278(5345):1943-7. PMID:9395396

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