4b3z | pdb_00004b3z

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Template:STRUCTURE 4b3z

Structure of the human collapsin response mediator protein-1, a lung cancer suppressor

Function

[DPYL1_HUMAN] Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration.[1]

About this Structure

4b3z is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. ↑ Shih JY, Yang SC, Hong TM, Yuan A, Chen JJ, Yu CJ, Chang YL, Lee YC, Peck K, Wu CW, Yang PC. Collapsin response mediator protein-1 and the invasion and metastasis of cancer cells. J Natl Cancer Inst. 2001 Sep 19;93(18):1392-400. PMID:11562390

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