4jvs | pdb_00004jvs

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Template:STRUCTURE 4jvs

Crystal structure of LepB GAP domain from Legionella drancourtii in complex with Rab1-GDP and AlF3

Template:ABSTRACT PUBMED 23588383

Function

[RAB1A_HUMAN] Probably required for transit of protein from the ER through Golgi compartment. Binds GTP and GDP and possesses intrinsic GTPase activity.

About this Structure

4jvs is a 2 chain structure with sequence from Homo sapiens and Legionella drancourtii llap12. Full crystallographic information is available from OCA.

Reference

  1. Yu Q, Hu L, Yao Q, Zhu Y, Dong N, Wang DC, Shao F. Structural analyses of Legionella LepB reveal a new GAP fold that catalytically mimics eukaryotic RasGAP. Cell Res. 2013 Apr 16. doi: 10.1038/cr.2013.54. PMID:23588383 doi:10.1038/cr.2013.54

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OCA