4bx9 | pdb_00004bx9

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Template:STRUCTURE 4bx9

Human Vps33A in complex with a fragment of human Vps16

Template:ABSTRACT PUBMED 23901104

Function

[VP33A_HUMAN] May play a role in vesicle-mediated protein trafficking to lysosomal compartments and in membrane docking/fusion reactions of late endosomes/lysosomes (By similarity). [VPS16_HUMAN] May play a role in vesicle-mediated protein trafficking to lysosomal compartments and in membrane docking/fusion reactions of late endosomes/lysosomes.

About this Structure

4bx9 is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Graham SC, Wartosch L, Gray SR, Scourfield EJ, Deane JE, Luzio JP, Owen DJ. Structural basis of Vps33A recruitment to the human HOPS complex by Vps16. Proc Natl Acad Sci U S A. 2013 Jul 30. PMID:23901104 doi:10.1073/pnas.1307074110

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