3zot | pdb_00003zot

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Template:STRUCTURE 3zot

Structure of E.coli rhomboid protease GlpG in complex with monobactam L29 (data set 2)

Template:ABSTRACT PUBMED 23665170

Function

[GLPG_ECOLI] Rhomboid-type serine protease that catalyzes intramembrane proteolysis.[1] [2]

About this Structure

3zot is a 1 chain structure with sequence from Escherichia coli bl21(de3). Full crystallographic information is available from OCA.

See Also

Reference

  1. Vinothkumar KR, Pierrat OA, Large JM, Freeman M. Structure of Rhomboid Protease in Complex with beta-Lactam Inhibitors Defines the S2' Cavity. Structure. 2013 May 7. pii: S0969-2126(13)00117-2. doi:, 10.1016/j.str.2013.03.013. PMID:23665170 doi:10.1016/j.str.2013.03.013
  1. ↑ Wu Z, Yan N, Feng L, Oberstein A, Yan H, Baker RP, Gu L, Jeffrey PD, Urban S, Shi Y. Structural analysis of a rhomboid family intramembrane protease reveals a gating mechanism for substrate entry. Nat Struct Mol Biol. 2006 Dec;13(12):1084-91. Epub 2006 Nov 10. PMID:17099694 doi:10.1038/nsmb1179
  2. ↑ Maegawa S, Ito K, Akiyama Y. Proteolytic action of GlpG, a rhomboid protease in the Escherichia coli cytoplasmic membrane. Biochemistry. 2005 Oct 18;44(41):13543-52. PMID:16216077 doi:10.1021/bi051363k

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