4j6k | pdb_00004j6k

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Template:STRUCTURE 4j6k

Crystal structure of calcium2+-free wild-type CD23 lectin domain (crystal form B)

Template:ABSTRACT PUBMED 23933509

Function

[FCER2_HUMAN] Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specific antigen).

About this Structure

4j6k is a 8 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Dhaliwal B, Pang MO, Yuan D, Yahya N, Fabiane SM, McDonnell JM, Gould HJ, Beavil AJ, Sutton BJ. Conformational plasticity at the IgE-binding site of the B-cell receptor CD23. Mol Immunol. 2013 Aug 6;56(4):693-697. doi: 10.1016/j.molimm.2013.07.005. PMID:23933509 doi:10.1016/j.molimm.2013.07.005

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