4k6m | pdb_00004k6m

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Template:STRUCTURE 4k6m

Crystal Structure of the full-length Japanese encephalitis virus NS5

Function

[Q5NT71_9FLAV] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS000336_004_099774]

About this Structure

4k6m is a 2 chain structure with sequence from Japanese encephalitis virus. Full crystallographic information is available from OCA.

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