4l16 | pdb_00004l16

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Template:STRUCTURE 4l16

Crystal structure of FIGL-1 AAA domain in complex with ADP

Template:ABSTRACT PUBMED 23979136

Function

[FIGL1_CAEEL] Has a role in spindle assembly which acts in the progression through mitosis during embryogenesis. Required for fertility.[1]

About this Structure

4l16 is a 1 chain structure with sequence from Caenorhabditis elegans. Full crystallographic information is available from OCA.

Reference

  1. Peng W, Lin Z, Li W, Lu J, Shen Y, Wang C. Structural insights into unusually strong ATPase activity of the AAA domain of C. elegans fidgetin like-1 protein. J Biol Chem. 2013 Aug 26. PMID:23979136 doi:10.1074/jbc.M113.502559
  1. ↑ Luke-Glaser S, Pintard L, Tyers M, Peter M. The AAA-ATPase FIGL-1 controls mitotic progression, and its levels are regulated by the CUL-3MEL-26 E3 ligase in the C. elegans germ line. J Cell Sci. 2007 Sep 15;120(Pt 18):3179-87. PMID:17878235 doi:10.1242/jcs.015883

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