2bq1 | pdb_00002bq1
From Proteopedia
Ribonucleotide reductase class 1b holocomplex R1E,R2F from Salmonella typhimurium
Function
[RIR4_SALTY] Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. R2F contains the tyrosyl radical required for catalysis.
About this Structure
2bq1 is a 4 chain structure with sequence from Salmonella enterica subsp. enterica serovar typhimurium. Full crystallographic information is available from OCA.
See Also
Reference
- Uppsten M, Farnegardh M, Domkin V, Uhlin U. The first holocomplex structure of ribonucleotide reductase gives new insight into its mechanism of action. J Mol Biol. 2006 Jun 2;359(2):365-77. Epub 2006 Mar 31. PMID:16631785 doi:10.1016/j.jmb.2006.03.035
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Ribonucleoside-diphosphate reductase
- Salmonella enterica subsp. enterica serovar typhimurium
- Domkin, V.
- Farnegardh, M.
- Uhlin, U.
- Uppsten, M.
- Allosteric enzyme
- Allosteric regulation
- Asymmetric complex
- Atp-binding
- Class 1b
- Dna replication
- Holocomplex
- Iron
- Metal-binding
- Nucleotide-binding
- Oxidoreductase
- R1
- R1e
- R2
- R2f
- Radical transfer
- Ribonucleotide reductase