2r0l | pdb_00002r0l

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Template:STRUCTURE 2r0l

Short Form HGFA with Inhibitory Fab75

Template:ABSTRACT PUBMED 18077410

Function

[HGFA_HUMAN] Activates hepatocyte growth factor (HGF) by converting it from a single chain to a heterodimeric form.

About this Structure

2r0l is a 4 chain structure with sequence from [1], Homo sapiens and Ruellia. Full crystallographic information is available from OCA.

See Also

Reference

  1. Wu Y, Eigenbrot C, Liang WC, Stawicki S, Shia S, Fan B, Ganesan R, Lipari MT, Kirchhofer D. Structural insight into distinct mechanisms of protease inhibition by antibodies. Proc Natl Acad Sci U S A. 2007 Dec 11;104(50):19784-9. Epub 2007 Dec 5. PMID:18077410

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OCA

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