4mcd | pdb_00004mcd
From Proteopedia
hinTrmD in complex with 5-PHENYLTHIENO[2,3-D]PYRIMIDIN-4(3H)-ONE
Function
[TRMD_HAEIN] Specifically methylates guanosine-37 in various tRNAs (By similarity).[HAMAP-Rule:MF_00605]
About this Structure
4mcd is a 1 chain structure with sequence from Haemophilus influenzae rd kw20. Full crystallographic information is available from OCA.
Reference
- Hill PJ, Abibi A, Albert R, Andrews B, Gagnon MM, Gao N, Grebe T, Hajec LI, Huang J, Livchak S, Lahiri SD, McKinney DC, Thresher J, Wang H, Olivier N, Buurman ET. Selective Inhibitors of Bacterial t-RNA-(NG37) Methyltransferase (TrmD) that Demonstrate Novel Ordering of the Lid Domain. J Med Chem. 2013 Aug 27. PMID:23981144 doi:10.1021/jm400718n
