4m4w | pdb_00004m4w

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Template:STRUCTURE 4m4w

Mechanistic implications for the bacterial primosome assembly of the structure of a helicase-helicase loader complex

Template:ABSTRACT PUBMED 24048025

Function

[DNAI_BACSU] Probably involved in DNA replication. [PRIM_GEOSE] DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis.

About this Structure

4m4w is a 15 chain structure with sequence from Bacillus subtilis subsp. subtilis str. 168 and Geobacillus stearothermophilus. Full crystallographic information is available from OCA.

Reference

  1. Liu B, Eliason WK, Steitz TA. Structure of a helicase-helicase loader complex reveals insights into the mechanism of bacterial primosome assembly. Nat Commun. 2013;4:2495. doi: 10.1038/ncomms3495. PMID:24048025 doi:10.1038/ncomms3495

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OCA