2kw6 | pdb_00002kw6

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Template:STRUCTURE 2kw6

Solution NMR Structure of Cyclin-dependent kinase 2-associated protein 1 (CDK2-associated protein 1; oral cancer suppressor Deleted in oral cancer 1, DOC-1) from H.sapiens, Northeast Structural Genomics Consortium Target Target HR3057H

Template:ABSTRACT PUBMED 22427660

Function

[CDKA1_HUMAN] specific inhibitor of the cell-cycle kinase CDK2 (By similarity).

About this Structure

2kw6 is a 2 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA.

Reference

  1. Ertekin A, Aramini JM, Rossi P, Leonard PG, Janjua H, Xiao R, Maglaqui M, Lee HW, Prestegard JH, Montelione GT. Human cyclin-dependent kinase 2-associated protein 1 (CDK2AP1) is dimeric in its disulfide-reduced state, with natively disordered N-terminal region. J Biol Chem. 2012 May 11;287(20):16541-9. Epub 2012 Mar 14. PMID:22427660 doi:10.1074/jbc.M112.343863

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