4kwv | pdb_00004kwv

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Template:STRUCTURE 4kwv

Crystal Structure of human apo-QPRT

Template:ABSTRACT PUBMED 24038671

Function

[NADC_HUMAN] Involved in the catabolism of quinolinic acid (QA).[1]

About this Structure

4kwv is a 6 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Malik SS, Patterson DN, Ncube Z, Toth EA. The crystal structure of human quinolinic acid phosphoribosyltransferase in complex with its inhibitor phthalic acid. Proteins. 2013 Aug 28. doi: 10.1002/prot.24406. PMID:24038671 doi:10.1002/prot.24406
  1. ↑ Liu H, Woznica K, Catton G, Crawford A, Botting N, Naismith JH. Structural and kinetic characterization of quinolinate phosphoribosyltransferase (hQPRTase) from homo sapiens. J Mol Biol. 2007 Oct 26;373(3):755-63. Epub 2007 Aug 24. PMID:17868694 doi:10.1016/j.jmb.2007.08.043

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