4j6s | pdb_00004j6s
From Proteopedia
14-3-3gamma complexed with the N-terminal sequence of tyrosine hydroxylase (residues 1-43)
Function
[1433G_HUMAN] Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.[1]
About this Structure
4j6s is a 8 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- ↑ Jin Y, Dai MS, Lu SZ, Xu Y, Luo Z, Zhao Y, Lu H. 14-3-3gamma binds to MDMX that is phosphorylated by UV-activated Chk1, resulting in p53 activation. EMBO J. 2006 Mar 22;25(6):1207-18. Epub 2006 Mar 2. PMID:16511572 doi:10.1038/sj.emboj.7601010
