4bjk | pdb_00004bjk

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Template:STRUCTURE 4bjk

CYP51 of Trypanosoma brucei bound to (S)-N-(3-(1H-indol-3-yl)-1-oxo-1- (pyridin-4-ylamino)propan-2-yl)-3,3'-difluoro-(1,1'-biphenyl)-4- carboxamide

Template:ABSTRACT PUBMED 24079662

About this Structure

4bjk is a 4 chain structure with sequence from Trypanosoma brucei. Full crystallographic information is available from OCA.

Reference

  1. Choi JY, Calvet CM, Gunatilleke SS, Ruiz C, Cameron MD, McKerrow JH, Podust LM, Roush WR. Rational Development of 4-Aminopyridyl-Based Inhibitors Targeting Trypanosoma cruzi CYP51 as Anti-Chagas Agents. J Med Chem. 2013 Sep 30. PMID:24079662 doi:https://dx.doi.org/10.1021/jm401067s

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