4isr | pdb_00004isr
From Proteopedia
Binding domain of Botulinum neurotoxin DC in complex with rat synaptotagmin II
Template:ABSTRACT PUBMED 23932591
Function
[SYT2_RAT] May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone.
About this Structure
4isr is a 6 chain structure with sequence from Clostridium botulinum. Full crystallographic information is available from OCA.
Reference
- Berntsson RP, Peng L, Svensson LM, Dong M, Stenmark P. Crystal Structures of Botulinum Neurotoxin DC in Complex with Its Protein Receptors Synaptotagmin I and II. Structure. 2013 Sep 3;21(9):1602-11. doi: 10.1016/j.str.2013.06.026. Epub 2013, Aug 8. PMID:23932591 doi:https://dx.doi.org/10.1016/j.str.2013.06.026
