4bmd | pdb_00004bmd

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Template:STRUCTURE 4bmd

Crystal structure of S.pombe Rad4 BRCT3,4

Template:ABSTRACT PUBMED 24074952

Function

[RAD4_SCHPO] Essential component for DNA replication and also the checkpoint control system which couples S and M phases. May directly or indirectly interact with chromatin proteins to form the complex required for the initiation and/or progression of DNA synthesis.

About this Structure

4bmd is a 1 chain structure with sequence from Schizosaccharomyces pombe. Full crystallographic information is available from OCA.

Reference

  1. Qu M, Rappas M, Wardlaw CP, Garcia V, Ren JY, Day M, Carr AM, Oliver AW, Du LL, Pearl LH. Phosphorylation-Dependent Assembly and Coordination of the DNA Damage Checkpoint Apparatus by Rad4(TopBP1.). Mol Cell. 2013 Sep 26;51(6):723-36. doi: 10.1016/j.molcel.2013.08.030. PMID:24074952 doi:https://dx.doi.org/10.1016/j.molcel.2013.08.030

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