4m9r | pdb_00004m9r
From Proteopedia
Crystal structure of CED-3
Template:ABSTRACT PUBMED 24065769
Function
[CED3_CAEEL] Acts as a cysteine protease in controlling programmed cell death by proteolytically activating or inactivating a substrate protein or proteins, a potential substrate may be ced-4. Alternatively it might directly cause cell death by proteolytically cleaving proteins that are crucial for cell viability.
About this Structure
4m9r is a 2 chain structure with sequence from Caenorhabditis elegans. Full crystallographic information is available from OCA.
Reference
- Huang W, Jiang T, Choi W, Qi S, Pang Y, Hu Q, Xu Y, Gong X, Jeffrey PD, Wang J, Shi Y. Mechanistic insights into CED-4-mediated activation of CED-3. Genes Dev. 2013 Sep 15;27(18):2039-48. doi: 10.1101/gad.224428.113. PMID:24065769 doi:https://dx.doi.org/10.1101/gad.224428.113
