4khw | pdb_00004khw
From Proteopedia
Ternary complex of RB69 mutant L415F with ribonucleotide at -2 position
Template:ABSTRACT PUBMED 24082122
Function
[DPOL_BPR69] This polymerase possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single stranded DNA in the 3'- to 5'-direction.
About this Structure
4khw is a 3 chain structure with sequence from Enterobacteria phage rb69. Full crystallographic information is available from OCA.
Reference
- Clausen AR, Murray MS, Passer AR, Pedersen LC, Kunkel TA. Structure-function analysis of ribonucleotide bypass by B family DNA replicases. Proc Natl Acad Sci U S A. 2013 Oct 15;110(42):16802-7. doi:, 10.1073/pnas.1309119110. Epub 2013 Sep 30. PMID:24082122 doi:https://dx.doi.org/10.1073/pnas.1309119110
