4kp0 | pdb_00004kp0
From Proteopedia
Crystal Structure of the human Chymase with TJK002
Template:ABSTRACT PUBMED 24121339
Function
[CMA1_HUMAN] Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion.
About this Structure
4kp0 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Matsumoto Y, Kakuda S, Koizumi M, Mizuno T, Muroga Y, Kawamura T, Takimoto-Kamimura M. Crystal structure of a complex of human chymase with its benzimidazole derived inhibitor. J Synchrotron Radiat. 2013 Nov;20(Pt 6):914-8. doi: 10.1107/S0909049513020748., Epub 2013 Sep 25. PMID:24121339 doi:https://dx.doi.org/10.1107/S0909049513020748