4kp0 | pdb_00004kp0

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Template:STRUCTURE 4kp0

Crystal Structure of the human Chymase with TJK002

Template:ABSTRACT PUBMED 24121339

Function

[CMA1_HUMAN] Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion.

About this Structure

4kp0 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Matsumoto Y, Kakuda S, Koizumi M, Mizuno T, Muroga Y, Kawamura T, Takimoto-Kamimura M. Crystal structure of a complex of human chymase with its benzimidazole derived inhibitor. J Synchrotron Radiat. 2013 Nov;20(Pt 6):914-8. doi: 10.1107/S0909049513020748., Epub 2013 Sep 25. PMID:24121339 doi:https://dx.doi.org/10.1107/S0909049513020748

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