4lpb | pdb_00004lpb

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Template:STRUCTURE 4lpb

Crystal structure of a topoisomerase ATPase inhibitor

Template:ABSTRACT PUBMED 24098982

About this Structure

4lpb is a 1 chain structure with sequence from Streptococcus pneumoniae r6. Full crystallographic information is available from OCA.

Reference

  1. Basarab GS, Manchester JI, Bist S, Boriack-Sjodin PA, Dangel B, Illingworth R, Sherer BA, Sriram S, Uria-Nickelsen M, Eakin AE. Fragment-to-Hit-to-Lead Discovery of a Novel Pyridylurea Scaffold of ATP Competitive Dual Targeting Type II Topoisomerase Inhibiting Antibacterial Agents. J Med Chem. 2013 Oct 29. PMID:24098982 doi:https://dx.doi.org/10.1021/jm401208b

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